The use of levetiracetam in refractory status epilepticus

被引：74

作者：

Patel, NC

Landan, IR

Levin, J

Szaflarski, J

Wilner, AN

机构：

[1] Michigan State Univ, Saginaw, MI 48604 USA

[2] Univ Cincinnati, Med Ctr, Dept Neurol, Cincinnati, OH 45267 USA

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2006年 / 15卷 / 03期

关键词：

status epilepticus; levetiracetam; antiepileptic drugs;

D O I：

10.1016/j.seizure.2005.12.003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Six patients with status epitepticus (SE) of various etiologies refractory to at least two antiepileptic drugs (AEDs) had complete cessation of their seizures following administration of oral levetiracetam (LEY). Seizure types included convulsive, focal, and nonconvulsive status epilepticus. Effective doses of levetiracetam ranged from 500 to 3000 mg/day, achieving seizure control within 12-96 h. No significant adverse events were noted. Adjunctive levetiracetam should be considered for patients with status epitepticus unresponsive to initial therapy. (c) 2005 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

引用

收藏

页码：137 / 141

页数：5

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