Relation Between Optimism and Lipids in Midlife

被引:67
作者
Boehm, Julia K. [1 ]
Williams, David R. [1 ,2 ]
Rimm, Eric B. [3 ,4 ,5 ,6 ]
Ryff, Carol [7 ,8 ]
Kubzansky, Laura D. [1 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 USA
[2] Harvard Univ, Dept African & African Amer Studies & Sociol, Boston, MA 02115 USA
[3] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[4] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[5] Brigham & Womens Hosp, Channing Lab, Dept Med, Boston, MA 02115 USA
[6] Harvard Univ, Sch Med, Boston, MA 02115 USA
[7] Univ Wisconsin, Dept Psychol, Madison, WI 53706 USA
[8] Univ Wisconsin, Inst Aging, Madison, WI USA
基金
美国国家卫生研究院;
关键词
DENSITY-LIPOPROTEIN CHOLESTEROL; DISPOSITIONAL OPTIMISM; OLDER MEN; INFLAMMATION; EXERCISE; HEALTH; ASSOCIATIONS; DISEASE; ADULTS;
D O I
10.1016/j.amjcard.2013.01.292
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
The present research examined optimism's relation with total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides. The hypothesis that optimism is associated with a healthier lipid profile was tested. The participants were 990 mostly white men and women from the Mid life in the United States study, who were, on average, 55.1 years old. Optimism was assessed by self-report using the Life Orientation Test. A fasting blood sample was used to assess the serum lipid levels. Linear and logistic regression models examined the cross-sectional association between optimism and lipid levels, accounting for covariates such as demographic characteristics (e.g., education) and health status (e.g., chronic medical conditions). After adjusting for covariates, the results suggested that greater optimism was associated with greater high-density lipoprotein cholesterol and lower triglycerides. Optimism was not associated with low-density lipoprotein or total cholesterol. The findings were robust to a variety of modeling strategies that considered the effect of treatment of cholesterol problems. The results also indicated that diet and body mass index might link optimism with lipids. In conclusion, this is the first study to suggest that optimism is associated with a healthy lipid profile; moreover, these associations can be explained, in part, by the presence of healthier behaviors and a lower body mass index. (c) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:1425 / 1431
页数:7
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