The UCSC Genome Browser Database: update 2009

被引:280
作者
Kuhn, R. M. [1 ]
Karolchik, D. [1 ]
Zweig, A. S. [1 ]
Wang, T. [1 ]
Smith, K. E. [1 ]
Rosenbloom, K. R. [1 ]
Rhead, B. [1 ]
Raney, B. J. [1 ]
Pohl, A. [1 ]
Pheasant, M. [1 ]
Meyer, L. [1 ]
Hsu, F. [1 ]
Hinrichs, A. S. [1 ]
Harte, R. A. [1 ]
Giardine, B. [2 ]
Fujita, P. [1 ]
Diekhans, M. [1 ]
Dreszer, T. [1 ]
Clawson, H. [1 ]
Barber, G. P. [1 ]
Haussler, D. [1 ,3 ]
Kent, W. J. [1 ]
机构
[1] Univ Calif Santa Cruz, Ctr Biomol Sci & Engn, Sch Engn, Santa Cruz, CA 95064 USA
[2] Penn State Univ, Huck Inst Life Sci, Ctr Comparat Genom & Bioinformat, University Pk, PA 16802 USA
[3] Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA
关键词
MOUSE; SEQUENCES; RESOURCE;
D O I
10.1093/nar/gkn875
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The UCSC Genome Browser Database (GBD, http://genome.ucsc.edu) is a publicly available collection of genome assembly sequence data and integrated annotations for a large number of organisms, including extensive comparative-genomic resources. In the past year, 13 new genome assemblies have been added, including two important primate species, orangutan and marmoset, bringing the total to 46 assemblies for 24 different vertebrates and 39 assemblies for 22 different invertebrate animals. The GBD datasets may be viewed graphically with the UCSC Genome Browser, which uses a coordinate-based display system allowing users to juxtapose a wide variety of data. These data include all mRNAs from GenBank mapped to all organisms, RefSeq alignments, gene predictions, regulatory elements, gene expression data, repeats, SNPs and other variation data, as well as pairwise and multiple-genome alignments. A variety of other bioinformatics tools are also provided, including BLAT, the Table Browser, the Gene Sorter, the Proteome Browser, VisiGene and Genome Graphs.
引用
收藏
页码:D755 / D761
页数:7
相关论文
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