IC202B and C, new siderophores with immunosuppressive activity produced by Streptoalloteichus sp 1454-19

被引：9

作者：

Iijima, M

Someno, T

Ishizuka, M

Sawa, R

Naganawa, H

Takeuchi, T

机构：

[1] MCRF, Inst Chemotherapy, Numazu, Shizuoka 4100301, Japan

[2] MCRF, Inst Microbial Chem, Shinagawa Ku, Tokyo 1410021, Japan

来源：

JOURNAL OF ANTIBIOTICS | 1999年 / 52卷 / 09期

关键词：

D O I：

10.7164/antibiotics.52.775

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

IC202B (1) and C (2) were isolated from the culture filtrate of Streptoalloteichus sp. 1454-19. The structures were elucidated by various NMR spectral analyses including H-1-N-15 HMBC and FAB-MS experiments. IC202B and C showed immunosuppressive activity on a mixed lymphocyte culture reaction at the same IC50 value of 1.6 mu g/ml.

引用

页码：775 / 780

页数：6

共 5 条

[1] EFFECT OF AN IRON-CHELATING AGENT ON LYMPHOCYTE-PROLIFERATION [J].