Myoglobin content in skeletal muscles of hibernating ground squirrels rises in autumn and winter

被引：23

作者：

Postnikova, GB ^{[1
]}

Tselikova, SV

Kolaeva, SG

Solomonov, NG

机构：

[1] Russian Acad Sci, Inst Cell Biophys, Grp Biophys Redox Prot, Lab Hypometab States, Pushchino 142292, Moscow Region, Russia

[2] Russian Acad Sci, Inst Biol, Siberian Dept, Yakutsk 877007, Russia

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY | 1999年 / 124卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

seasonal changes; myoglobin content; oxygen supply; ground squirrel; hibernation;

D O I：

10.1016/S1095-6433(99)00085-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The content of myoglobin (Mb) in skeletal muscles of Arctic Yakutian ground squirrel (Citellus undulatus Pallas) was measured in the active euthermic summer and prehibernating autumn animals as well as in hibernating and awake animals in winter. The myoglobin content in winter, irrespective of the state of the animal, was found to be about three times higher than in summer. The content of myoglobin in autumn was also two-fold increased compared to summer, suggesting that high myoglobin level is necessary for hibernation. Analysis of biochemical data available suggests that the increase in myoglobin content in winter is probably related to a high oxygen demand of muscles at the first stage of arousal (non-shivering thermogenesis) when rectal temperature rises from 0 to 10-12 degrees C, At this stage, the oxygen-dependent processes in muscles proceed under the conditions when peripheral blood flow is blocked and anaerobic glycolysis is switched off. (C) 1999 Elsevier Science Inc. All rights reserved.

引用

页码：35 / 37

页数：3

共 14 条

[1]

AMBID L, 1975, CR SOC BIOL, V169, P1380

[2]

ANTONINI E, 1971, FRONT BIOL, P1

[3]

CHUPAKHINA V L, 1990, Fiziologicheskii Zhurnal SSSR Imeni I M Sechenova, V76, P406

[4] BLOCKADE OF AROUSAL FROM HIBERNATION BY INHIBITION OF NOREPINERPHRINE SYNTHESIS IN GOLDEN HAMSTER [J].

FEIST, DD .

LIFE SCIENCE PART 1 PHYSIOLOGY & PHARMACOLOGY, 1970, 9 (19) :1117-+

[5]

IVANOV KP, 1961, B EXP BIOL MED+, V51, P12

[6]

KAYSER C, 1961, PHYSL NATURAL HIBERN, P60

[7]

KOROBOV VN, 1993, USP SOVREM BIOL, V113, P60

[8]

LYMAN C, 1982, HIBERNATION TORPOR M, P265

[9] SEASONAL VARIATION OF MYOGLOBIN IN NORTHERN RED-BACKED VOLE [J].

MORRISON, P ;

ROSENMANN, M ;

SEALANDER, JA .

AMERICAN JOURNAL OF PHYSIOLOGY, 1966, 211 (06) :1305-+

[10]

MUSACCHIA X, 1989, LIVING COLD, V2, P217

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