Dynamics of transient pores in stretched vesicles

被引:317
作者
Sandre, O
Moreaux, L
Brochard-Wyart, F
机构
[1] Inst Curie, UMR 168 CNRS, Lab Physciochim Curie, F-75248 Paris 05, France
[2] Ecole Super Phys & Chim Ind, CNRS 7637, Physiol Lab, F-75248 Paris, France
关键词
D O I
10.1073/pnas.96.19.10591
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
We image macroscopic transient pores in mechanically stretched giant vesicles. Holes open above a critical radius r(c1), grow up to a radius r(c2), and close. We interpret the upper limit r(c2) by a relaxation of the membrane tension as the holes expand. The closing of the holes is caused by a further relaxation of the surface tension when the internal liquid leaks out. A dynamic model fits our data for the growth and closure of pores.
引用
收藏
页码:10591 / 10596
页数:6
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