Structure determination and synthesis of a new cerebroside isolated from the traditional Chinese medicine Typhonium giganteum Engl.

被引：46

作者：

Chen, XS

Wu, YL

Chen, DH

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

[2] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China

[3] Beijing Union Med Coll, Beijing 100094, Peoples R China

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 19期

基金：

中国国家自然科学基金;

关键词：

Typhonium giganteum; Engl; cerebroside; typhoniside;

D O I：

10.1016/S0040-4039(02)00583-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new cerebroside with C18-4,8-sphingadienine as the long chain base has been isolated from the traditional Chinese medicine Typhonium giganteum Enal., and its structure was determined by 2D NMR and MS methods. It was then synthesized using D-xylose and ascorbic acid as the chiral starting materials. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：3529 / 3532

页数：4

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