Morphogen gradients - New insights from DPP

被引:99
作者
Podos, SD [1 ]
Ferguson, EL [1 ]
机构
[1] Univ Chicago, Dept Mol Genet & Cell Biol, Chicago, IL 60637 USA
关键词
D O I
10.1016/S0168-9525(99)01854-5
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The Drosophila TGF beta family member Decapentaplegic (DPP) has been proposed to function as a morphogen to pattern cell fields in a number of developmental contexts. A series of recent: reports add significantly to our knowledge of the mechanisms of DPP-gradient formation and interpretation. These reports identify additional genes and genetic circuitry necessary for this patterning system, and they highlight variations that might reflect developmental constraints within individual target cell fields.
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页码:396 / 402
页数:7
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