Genetic polymorphisms of UDP-glucuronosyltransferase in Asians:: UGT1A1*28 is a common allele in Indians

被引:48
作者
Balram, C
Sabapathy, K
Fei, G
Khoo, KS
Lee, EJD
机构
[1] Natl Univ Singapore, Fac Med, Dept Pharmacol, Singapore 117597, Singapore
[2] Natl Canc Ctr, Lab Clin Pharmacol, Singapore, Singapore
[3] Natl Canc Ctr, Mol Carcinogenesis Lab, Singapore, Singapore
[4] Natl Canc Ctr, Div Clin Trials & Epidemiol Sci, Biostat Unit, Singapore, Singapore
来源
PHARMACOGENETICS | 2002年 / 12卷 / 01期
关键词
UGT1A1; gene; Asian population; serum bilirubin; polymorphism;
D O I
10.1097/00008571-200201000-00012
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
[No abstract available]
引用
收藏
页码:81 / 83
页数:3
相关论文
共 11 条
[1]   The UGT1A1*28 allele is relatively rare in a Japanese population [J].
Ando, Y ;
Chida, M ;
Nakayama, K ;
Saka, H ;
Kamataki, T .
PHARMACOGENETICS, 1998, 8 (04) :357-360
[2]   IDENTIFICATION OF DEFECT IN THE GENES FOR BILIRUBIN UDP-GLUCURONOSYL-TRANSFERASE IN A PATIENT WITH CRIGLER-NAJJAR SYNDROME TYPE-II [J].
AONO, S ;
YAMADA, Y ;
KEINO, H ;
HANADA, N ;
NAKAGAWA, T ;
SASAOKA, Y ;
YAZAWA, T ;
SATO, H ;
KOIWAI, O .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 197 (03) :1239-1244
[3]   Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter:: A balanced polymorphism for regulation of bilirubin metabolism? [J].
Beutler, E ;
Gelbart, T ;
Demina, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (14) :8170-8174
[4]   MECHANISMS OF INHERITED DEFICIENCIES OF MULTIPLE UDP-GLUCURONOSYLTRANSFERASE ISOFORMS IN 2 PATIENTS WITH CRIGLER-NAJJAR SYNDROME, TYPE-I [J].
BOSMA, PJ ;
CHOWDHURY, JR ;
HUANG, TJ ;
LAHIRI, P ;
ELFERINK, RPJO ;
VANES, HHG ;
LEDERSTEIN, M ;
WHITINGTON, PF ;
JANSEN, PLM ;
CHOWDHURY, NR .
FASEB JOURNAL, 1992, 6 (10) :2859-2863
[5]   ETHNIC DIFFERENCES IN NEONATAL JAUNDICE - COMPARISON OF JAPANESE AND CAUCASIAN NEWBORN-INFANTS [J].
HORIGUCHI, T ;
BAUER, C .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1975, 121 (01) :71-74
[6]   Variations of the bilirubin uridine-diphosyphoglucuronosyl transferase 1A1 gene in healthy Taiwanese [J].
Huang, CS ;
Luo, GA ;
Huang, MJ ;
Yu, SC ;
Yang, SS .
PHARMACOGENETICS, 2000, 10 (06) :539-544
[7]   UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians:: relationships to serum bilirubin concentrations [J].
Lampe, JW ;
Bigler, J ;
Horner, NK ;
Potter, JD .
PHARMACOGENETICS, 1999, 9 (03) :341-349
[8]   UGT1*1 genotyping in a Canadian Inuit population [J].
Monaghan, G ;
Foster, B ;
JurimaRomet, M ;
Hume, R ;
Burchell, B .
PHARMACOGENETICS, 1997, 7 (02) :153-156
[9]   Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome [J].
Monaghan, G ;
Ryan, M ;
Seddon, R ;
Hume, R ;
Burchell, B .
LANCET, 1996, 347 (9001) :578-581
[10]   POPULATION STUDIES ON GILBERTS-SYNDROME [J].
OWENS, D ;
EVANS, J .
JOURNAL OF MEDICAL GENETICS, 1975, 12 (02) :152-156