Asthma and the elite athlete: Summary of the International Olympic Committee's Consensus Conference, Lausanne, Switzerland, January 22-24, 2008

被引:157
作者
Fitch, Kenneth D. [1 ]
Sue-Chu, Malcolm [2 ,3 ]
Anderson, Sandra D. [4 ]
Boulet, Louis-Philippe [5 ]
Hancox, Robert J. [6 ,7 ]
McKenzie, Donald C. [8 ,9 ]
Backer, Vibeke [10 ]
Rundell, Kenneth W. [11 ]
Alonso, Juan M. [12 ]
Kippelen, Pascale [13 ]
Cummiskey, Joseph M. [14 ]
Garnier, Alain [15 ]
Ljungqvist, Arne [16 ]
机构
[1] Univ Western Australia, Sch Sports Sci Exercise & Hlth, Fac Life Sci, Crawley, WA, Australia
[2] Univ Trondheim Hosp, Dept Lung Med, St Olays Hosp, Trondheim, Norway
[3] Norwegian Univ Sci & Technol, Dept Circulat & Imaging, Trondheim, Norway
[4] Royal Prince Alfred Hosp, Dept Resp & Sleep Med, Camperdown, NSW 2050, Australia
[5] Univ Laval, Hop Laval, Inst Cardiol & Pneumol, Quebec City, PQ G1K 7P4, Canada
[6] Univ Otago, Dunedin Sch Med, Dept Prevent & Social Med, Christchurch, New Zealand
[7] Waikato Hosp, Dept Resp Med, Hamilton, New Zealand
[8] Univ British Columbia, Div Sports Med, Vancouver, BC V5Z 1M9, Canada
[9] Univ British Columbia, Sch Human Kinet, Vancouver, BC V5Z 1M9, Canada
[10] Bispebjerg Hosp, Dept Resp Med L, Copenhagen, Denmark
[11] Marywood Univ, Human Physiol Lab, Scranton, PA USA
[12] Int Assoc Athlet Federat, Monaco, Monaco
[13] Univ Aberdeen, Sch Med Sci, Aberdeen AB9 1FX, Scotland
[14] Blackrock Clin, Dublin, Ireland
[15] World Antidoping Agcy, Lausanne, Switzerland
[16] Int Olymp Comm, Lausanne, Switzerland
关键词
respiratory symptoms; exercise-induced bronchoconstriction; asthma; beta(2)-agonists; airway hyperresponsiveness; bronchial provocation; Olympic Games; endurance training; environment;
D O I
10.1016/j.jaci.2008.07.003
中图分类号
R392 [医学免疫学];
学科分类号
100102 [免疫学];
摘要
Respiratory symptoms cannot be relied on to make a diagnosis of asthma and/or airways hyperresponsiveness (AHR) in elite athletes. For this reason, the diagnosis should be confirmed with bronchial provocation tests. Asthma management in elite athletes should follow established treatment guidelines (eg, Global Initiative for Asthma) and should include education, an. individually tailored treatment plan, minimization of aggravating environmental factors, and appropriate drug therapy that must meet the requirements of the World Anti-Doping Agency. Asthma control can usually be achieved with inhaled corticosteroids and inhaled beta(2)-agonists to minimize exercise-induced bronchoconstriction and to treat intermittent symptoms. The rapid development of tachyphylaxis to beta(2)-agonists after regular daily. use poses a dilemma for athletes. Long-term intense endurance training, particularly in unfavorable environmental conditions, appears to be associated with an increased risk of developing asthma and AHR in elite athletes. Globally, the prevalence of asthma, exercise-induced bronchoconstriction, and AHR in Olympic athletes reflects the known prevalence of asthma symptoms in each country. The policy of requiring Olympic athletes to demonstrate the presence of asthma, exercise-induced bronchoconstriction, or AHR to be approved to inhale beta(2)-agonists will continue.
引用
收藏
页码:254 / 260
页数:7
相关论文
共 93 条
[1]
Asthma medication in Finnish Olympic athletes:: No signs of inhaled β2-agonist overuse [J].
Alaranta, A ;
Alaranta, H ;
Palmu, P ;
Alha, P ;
Pietila, K ;
Heliövaara, M ;
Helenius, I .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2004, 36 (06) :919-924
[2]
Anderson SD, 2005, EUR RESPIR MONOGR, P48
[3]
β2-agonists and exercise-induced asthma [J].
Anderson, Sandra D. ;
Caillaud, Corinne ;
Brannan, John D. .
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2006, 31 (2-3) :163-180
[4]
Anderson Sandra D, 2004, Treat Respir Med, V3, P365, DOI 10.2165/00151829-200403060-00004
[5]
The mechanism of exercise-induced asthma is ... [J].
Anderson, SD ;
Daviskas, E .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 106 (03) :453-459
[6]
ANDERSON SD, 1982, EUR J RESPIR DIS, V63, P459
[7]
Bronchial challenges in athletes applying to inhale a β2-agonist at the 2004 Summer Olympics [J].
Anderson, SD ;
Sue-Chu, M ;
Perry, CP ;
Gratziou, C ;
Kippelen, P ;
McKenzie, DC ;
Beck, KC ;
Fitch, KD .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (04) :767-773
[8]
Exercise-induced bronchoconstriction: Pathogenesis [J].
Anderson, SD ;
Kippelen, P .
CURRENT ALLERGY AND ASTHMA REPORTS, 2005, 5 (02) :116-122
[9]
Responses to bronchial challenge submitted for approval to use inhaled β2-agonists before an event at the 2002 Winter Olympics [J].
Anderson, SD ;
Fitch, K ;
Perry, CP ;
Sue-Chu, M ;
Crapo, R ;
McKenzie, D ;
Magnussen, H .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2003, 111 (01) :45-50
[10]
Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction [J].
Anderson, SD ;
Argyros, GJ ;
Magnussen, H ;
Holzer, K .
BRITISH JOURNAL OF SPORTS MEDICINE, 2001, 35 (05) :344-347