Abnormal lipids and the acquired immunodeficiency syndrome: is there a problem and what should we do about it?

被引：10

作者：

Crook, MA ^{[1
]}

Mir, N ^{[1
]}

机构：

[1] Guys & St Thomas Hosp, Dept Chem Pathol, London SE1 9RT, England

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 1999年 / 10卷 / 06期

关键词：

AIDS; lipids; cardiovascular disease; protease inhibitors; insulin resistance;

D O I：

10.1258/0956462991914212

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent research has shown abnormal lipids in acquired immunodeficiency syndrome (AIDS). In human immunodeficiency virus (HIV) infection hypocholesterolaemia, hypertriglyceridaemia and also low high density lipoprotein (HDL)-cholesterol have all been described. In addition, increased dense low density lipoprotein (EDL) particles and also lipoprotein (a) have been observed in some patients. The use of the protease inhibitors has been associated with diabetes mellitus and also features of insulin resistance. This article looks at these lipid abnormalities in detail and discusses possible therapeutic options that may be available, in order to address them.

引用

页码：353 / 356

页数：4

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