Hypertrophic cardiomyopathy and mtDNA depletion.: Successful treatment with heart transplantation

被引：23

作者：

Santorelli, FM

Gagliardi, MG

Dionisi-Vici, C

Parisi, F

Tessa, A

Carrozzo, R

Piemonte, F

Pfeiffer, K

Schägger, H

Bertini, E

机构：

[1] Bambino Gesu Hosp & Res Inst, Div Cardiol, I-00165 Rome, Italy

[2] Bambino Gesu Hosp & Res Inst, Div Neurol, I-00165 Rome, Italy

[3] Bambino Gesu Hosp & Res Inst, Div Metab, I-00165 Rome, Italy

[4] Bambino Gesu Hosp & Res Inst, Mol Med Unit, I-00165 Rome, Italy

[5] Univ Frankfurt Klinikum, D-60590 Frankfurt, Germany

来源：

NEUROMUSCULAR DISORDERS | 2002年 / 12卷 / 01期

关键词：

hypertrophic cardiomyopathy; mitochondrial DNA depletion; heart transplantation;

D O I：

10.1016/S0960-8966(01)00248-6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Cardiomyopathy associated with a mitochondrial DNA depletion syndrome is a rare condition. We report on a child with a hypertrophic cardiomyopathy and a mitochondrial depletion syndrome who was successfully treated by heart transplantation, given the tissue-specific nature of her mitochondrial disorder. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：56 / 59

页数：4

共 11 条

[1] Fatal neonatal liver failure and depletion of mitochondrial DNA in three children of one family [J].