In vivo evidence for brain-to-blood efflux transport of valproic acid across the blood-brain barrier

被引:20
作者
Kakee, A [1 ]
Takanaga, H
Hosoya, K
Sugiyama, Y
Terasaki, T
机构
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
[2] Tohoku Univ, Dept Mol Biopharm & Genet, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808579, Japan
[3] Tohoku Univ, New Ind Creat Hatchery Ctr, Aoba Ku, Sendai, Miyagi 9808579, Japan
[4] Japan Sci & Technol Corp, CREST, Tsukuba, Ibaraki, Japan
关键词
brain efflux index (BEI); blood-brain barrier; valproic acid; efflux transport;
D O I
10.1006/mvre.2001.2378
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
[No abstract available]
引用
收藏
页码:233 / 238
页数:6
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