Comparative in vitro activities of five quinolone antibiotics, including gemifloxacin, against clinical isolates

被引：7

作者：

Gönüllü, N

Aktas, Z

Salcioglu, M

Bal, Ç ^{[1
]}

Ang, Ö

机构：

[1] Univ Istanbul, Expt Med Res Inst, Istanbul, Turkey

[2] Univ Istanbul, Istanbul Fac Med, Dept Microbiol & Clin Microbiol, TR-34390 Istanbul, Turkey

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2001年 / 7卷 / 09期

关键词：

fluoroquinolones; gemifloxacin; MIC;

D O I：

10.1046/j.1198-743x.2001.00297.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The in vitro activities of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin and gemifloxacin against 343 clinical isolates were compared. Gemifloxacin showed the greatest activity, with MIC90 values as low as 0.03-0.25 mg/L against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, methicillin-susceptible Staphylococcus aureus and Klebsiella pneumoniae, while methicillin-resistant Staphylococcus aureus, Enterococcus spp., Pseudomonas spp., Acinetobacter spp., Escherichia coli and Enterobacter spp. strains exhibited low rates of susceptibility to all five fluoroquinolones.

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收藏

页码：499 / 503

页数：5

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