Linking chordate gene networks to cellular behavior in ascidians

被引：14

作者：

Davidson, B ^{[1
]}

Christiaen, L ^{[1
]}

机构：

[1] Univ Calif Berkeley, Div Genet & Dev, Dept Mol & Cellular Biol, Berkeley, CA 94720 USA

来源：

CELL | 2006年 / 124卷 / 02期

关键词：

D O I：

10.1016/j.cell.2006.01.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Embryos of simple chordates called ascidians (sea squirts) have few cells, develop rapidly, and are transparent, enabling the in vivo fluorescent imaging of labeled cell lineages. Ascidians are also simple genetically, with limited redundancy and compact regulatory regions. This cellular and genetic simplicity is now being exploited to link comprehensive gene networks to the cellular events underlying morphogenesis.

引用

页码：247 / 250

页数：4

共 15 条

[1]

Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors [J].

Bertrand, V ;

Hudson, C ;

Caillol, D ;

Popovici, C ;

Lemaire, P .

CELL, 2003, 115 (05) :615-627

[2]

Uncoupling heart cell specification and migration in the simple chordate Ciona intestinalis [J].

Davidson, B ;

Shi, WY ;

Levine, M .

DEVELOPMENT, 2005, 132 (21) :4811-4818

[3]

Germ-layer specification and control of cell growth by ectodermin, a Smad4 ubiquitin ligase [J].

Dupont, S ;

Zacchigna, L ;

Cordenonsi, M ;

Soligo, S ;

Adorno, M ;

Rugge, M ;

Piccolo, S .

CELL, 2005, 121 (01) :87-99

[4]

Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks [J].

Imai, KS ;

Hino, K ;

Yagi, K ;

Satoh, N ;

Satou, Y .

DEVELOPMENT, 2004, 131 (16) :4047-4058

[5]

Jiang D, 2005, CURR BIOL, V15, P79

[6]

Munro EM, 2002, DEVELOPMENT, V129, P13

[7]

Munro EM, 2002, DEVELOPMENT, V129, P1

[8]

POPK-1/Sad-1 kinase is required for the proper translocation of maternal mRNAs and putative germ plasm at the posterior pole of the ascidian embryo [J].

Nakamura, Y ;

Makabe, KW ;

Nishida, H .

DEVELOPMENT, 2005, 132 (21) :4731-4742

[9]

Specification of embryonic axis and mosaic development in ascidians [J].

Nishida, H .

DEVELOPMENTAL DYNAMICS, 2005, 233 (04) :1177-1193

[10]

macho-1 encodes a localized mRNA in ascidian eggs that specifies muscle fate during embryogenesis [J].

Nishida, H ;

Sawada, K .

NATURE, 2001, 409 (6821) :724-729

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