Pathogenesis and Management of Sarcopenia

被引:308
作者
Dhillon, Robinder J. S. [1 ]
Hasni, Sarfaraz [1 ]
机构
[1] NIAMSD, NIH, 9000 Rockville Pike,Bldg 10,Room 3-2340, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
Sarcopenia; Muscle strength; Muscle atrophy; Frailty; Aging; Senescence; Fall risk; Skeletal muscle mass; DWELLING OLDER-ADULTS; BODY-COMPOSITION; TRANSFORMING AGENT; MUSCLE MASS; CACHEXIA; DEFINITION; PREVALENCE; DIAGNOSIS; OBESITY; PEOPLE;
D O I
10.1016/j.cger.2016.08.002
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Sarcopenia represents a loss of muscle strength and mass in older individuals. Sarcopenia in the elderly has now become a major focus of research and public policy debate due to its impact on morbidity, mortality, and health care expenditure. Despite its clinical importance, sarcopenia remains under-recognized and poorly managed in routine clinical practice. This is, in part, due to a lack of available diagnostic testing and uniform diagnostic criteria. The management of sarcopenia is primarily focused on physical therapy for muscle strengthening and gait training. There are no pharmacologic agents for the treatment of sarcopenia.
引用
收藏
页码:17 / +
页数:11
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