Enzyme-Linked Immunosorbent Assay Method for Detection of Cytomegalovirus Strain-Specific Antibody Responses

被引：32

作者：

Novak, Zdenek ^{[1
]}

Ross, Shannon A. ^{[1
]}

Patro, Raj Kumar ^{[2
]}

Pati, Sunil Kumar ^{[2
]}

Reddy, Meera K. ^{[1
]}

Purser, Misty ^{[1
]}

Britt, William J. ^{[1
]}

Boppana, Suresh B. ^{[1
]}

机构：

[1] Univ Alabama, Dept Pediat, Birmingham, AL 35233 USA

[2] All India Inst Med Sci, New Delhi, India

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2009年 / 16卷 / 02期

关键词：

GLYCOPROTEIN-B; INFECTION; ASSOCIATION; WOMEN; GENOTYPES; EPITOPES; GP116;

D O I：

10.1128/CVI.00281-08

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Reliable methods for the detection of cytomegalovirus (CMV) strain-specific serological responses are lacking. We describe a simple and reliable enzyme-linked immunosorbent assay method developed to detect antibodies against the polymorphic epitopes within the two envelope glycoproteins of CMV, glycoproteins H and B. This assay is useful for the detection of serologic responses to CMV strains and the identification of CMV reinfections.

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收藏

页码：288 / 290

页数：3

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