The development of a new catalytic process:: Bu3SnH-catalyzed reductive cyclization of enals and enones

被引：22

作者：

Hays, DS ^{[1
]}

Fu, GC ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

TETRAHEDRON | 1999年 / 55卷 / 29期

关键词：

catalysis; cyclisation; silicon and compounds; tin and compounds;

D O I：

10.1016/S0040-4020(99)00446-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By sequencing two known reactions, a new catalytic carbon-carbon bond-forming process, the Bu3SnH-catalyzed, PhSiH3-mediated reductive cyclization of enals and enones, has been developed. The addition of EtOH to the reactions leads to reproducibly good yields of the cyclized products; a rationale for including this additive is provided. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8815 / 8832

页数：18

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