Lignans from Arnica species

被引：27

作者：

Schmidt, Thomas J. ^{[1
]}

Stausberg, Sabine ^{[1
]}

Von Raison, Jeanette ^{[1
]}

Berner, Matthias ^{[1
]}

Willuhn, Guenter ^{[1
]}

机构：

[1] Univ Munster, Inst Pharmazeut Biol & Biotechnol, D-40225 Dusseldorf, Germany

来源：

NATURAL PRODUCT RESEARCH | 2006年 / 20卷 / 05期

关键词：

lignan; dibenzylbutyrolactone; dibenzylbutyrolactol; furofuran; Arnica; Asteraceae;

D O I：

10.1080/14786410500218591

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

From four Arnica species (A. angustifolia Vahl ssp. attenuata (Greene) Maguire, A. lonchophylla Greene ssp. lonchophylla Maguire (flowerheads), A. chamissonis Less. ssp. foliosa (Nutt.) Maguire, A. montana L. ( roots and rhizomes)) a total of twelve lignans of the furofuran-, dibenzylbutyrolactone- and dibenzylbutyrolactol-type were isolated. No report on lignans as constituents of Arnica species exists so far. Besides the known pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin and nortracheloside, six dibenzylbutyrolactol derivatives with different stereochemistry and substitution at C-9 were isolated and their structures elucidated by NMR spectroscopic and mass spectral analysis.

引用

页码：443 / 453

页数：11

共 29 条

[1]

ACHENBACH H, 1983, PHYTOCHEMISTRY, V22, P749

[2] C-13 NMR SPECTRAL INVESTIGATIONS .9. C-13 NMR-SPECTROSCOPY OF LIGNAN AND NEOLIGNAN DERIVATIVES [J].

AGRAWAL, PK ;

THAKUR, RS .

MAGNETIC RESONANCE IN CHEMISTRY, 1985, 23 (06) :389-418

[3]

[Anonymous], 1990, LIGNANS CHEM BBIOLOG

[4] Lignans and neolignans as lead compounds [J].

S. Apers ;

A. Vlietinck ;

L. Pieters .

Phytochemistry Reviews, 2003, 2 (3) :201-217

[5] LIGNANS FROM THE WOOD OF ABIES PINSAPO [J].

BARRERO, AF ;

HAIDOUR, A ;

DORADO, MM ;

GRAVALOS, DG ;

QUESADA, TG .

JOURNAL OF NATURAL PRODUCTS, 1994, 57 (06) :713-719

[6]

BERNER M, 1995, THESIS U DUSSELDORF

[7]

BUCKINGHAM J, 2005, DICT NATURAL PRODUCT

[8]

Dragendorff G, 1898, HEILPFLANZEN VERSCHI

[9] MASS SPECTROMETRIC FRAGMENTATION OF SOME LIGNANS [J].

DUFFIELD, AM .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1967, 4 (01) :16-&

[10]

FONSECA S F, 1978, Phytochemistry (Oxford), V17, P499, DOI 10.1016/S0031-9422(00)89347-4

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