Reduced Incidence of Lower-Extremity Amputations in People With Diabetes in Scotland A nationwide study

被引:84
作者
Kennon, Brian [1 ]
Leese, Graham P. [2 ]
Cochrane, Lynda [3 ]
Colhoun, Helen [4 ]
Wild, Sarah
Stang, Duncan [5 ]
Sattar, Naveed
Pearson, Donald [6 ]
Lindsay, Robert S.
Morris, Andrew D.
Livingstone, Shona
Young, Matthew [7 ]
McKnight, John [8 ]
Cunningham, Scott [9 ,10 ]
机构
[1] So Gen Hosp, Diabet & Endocrinol Dept, Glasgow G51 4TF, Lanark, Scotland
[2] Ninewells Hosp, Diabet & Endocrinol Dept, Dundee DD1 9SY, Tayside, Scotland
[3] Univ Dundee, Div Clin & Populat Sci & Educ, Dundee, Tayside, Scotland
[4] Univ Dundee, Ctr Mol Med, Clin Res Ctr, Publ Hlth Wellcome Trust, Dundee, Tayside, Scotland
[5] Hairmyres Hosp, Podiatry Dept, E Kilbride, Lanark, Scotland
[6] Univ Aberdeen, Diabet Kings Coll, Aberdeen, Grampian, Scotland
[7] Royal Infirm Edinburgh NHS Trust, Ctr Diabet, Edinburgh, Lothian, Scotland
[8] Western Gen Hosp, Ctr Diabet, Edinburgh, Lothian, Scotland
[9] Univ Dundee, Clin Technol Ctr, SCI Diabet Collaborat Ninewells Hosp, Dundee, Tayside, Scotland
[10] Univ Dundee, Clin Technol Ctr, Sch Med, Dundee, Tayside, Scotland
基金
英国惠康基金;
关键词
MAJOR AMPUTATIONS; POPULATION; REDUCTION; INDIVIDUALS; RATES;
D O I
10.2337/dc12-0511
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
OBJECTIVE-To establish the incidence of nontraumatic lower-extremity amputation (LEA) in people with diabetes in Scotland. RESEARCH DESIGN AND METHODS-This cohort study linked national morbidity records and diabetes datasets to establish the number of people with diabetes who underwent nontraumatic major and minor LEA in Scotland from 2004 to 2008. RESULTS-Two thousand three hundred eighty-two individuals with diabetes underwent a nontraumatic LEA between 2004 and 2008; 57.1% (n = 1,359) underwent major LEAs. The incidence of any LEA among persons with diabetes fell over the 5-year study period by 29.8% (3.04 per 1,000 in 2004 to 2.13 per 1,000 in 2008, P < 0.001). Major LEA rates decreased by 40.7% from 1.87 per 1,000 in 2004 to 1.11 per 1,000 in 2008 (P < 0.001). CONCLUSIONS-There has been a significant reduction in the incidence of LEA in persons with diabetes in Scotland between 2004 and 2008, principally explained by a reduction in major amputation.
引用
收藏
页码:2588 / 2590
页数:3
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