A simple and robust conductive graphite coating for sheathless electrospray emitters used in capillary electrophoresis/mass spectrometry

被引：93

作者：

Nilsson, S ^{[1
]}

Wetterhall, M ^{[1
]}

Bergquist, J ^{[1
]}

Nyholm, L ^{[1
]}

Markides, KE ^{[1
]}

机构：

[1] Uppsala Univ, Dept Analyt Chem, SE-75121 Uppsala, Sweden

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2001年 / 15卷 / 21期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1002/rcm.466

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A graphite-polyimide mixture was used as a conductive coating for sheathless electrospray emitters. The coating procedure described is simple and inexpensive compared to previously described methods. An investigation of the stability of the conductive coating carried out by electrochemical methods revealed good performances during oxidative stress. In addition, no decrease in emitter performance was seen during continuous electrospray in the positive electrospray mode for two weeks. Fast capillary electrophoresis with attomole sensitivity demonstrated the excellent performance of the described sheathless interface when used in conjunction with an orthogonal time-of-flight mass spectrometer. The overall simplicity, stability and low cost of this type of sheathless emitter make the described approach highly suitable for any on-column coupling of low flow rate separation techniques to a mass spectrometer. Copyright (C) 2001 John Wiley & Sons, Ltd.

引用

页码：1997 / 2000

页数：4

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