Neurocognitive models of aggression, the antisocial personality disorders, and psychopathy

被引:441
作者
Blair, RJR
机构
[1] UCL, Inst Cognit Neurosci, London WC1N 3AR, England
[2] UCL, Dept Psychol, London WC1N 3AR, England
关键词
aggression; amygdala; orbitofrontal cortex;
D O I
10.1136/jnnp.71.6.727
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This paper considers neurocognitive models of aggression and relates them to explanations of the antisocial personality disorders. Two forms of aggression are distinguished: reactive aggression elicited in response to frustration/threat and goal directed, instrumental aggression. It is argued that different forms of neurocognitive model are necessary to explain the emergence of these different forms of aggression. Impairments in executive emotional systems (the somatic marker system or the social response reversal system) are related to reactive aggression shown by patients with "acquired sociopathy" due to orbitofrontal cortex lesions. Impairment in the capacity to form associations between emotional unconditioned stimuli, particularly distress cues, and conditioned stimuli (the violence inhibition mechanism model) is related to the instrumental aggression shown by persons with developmental psychopathy.
引用
收藏
页码:727 / 731
页数:5
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