Solution-phase synthesis of a beta-amino alcohol combinatorial library

被引：101

作者：

Chng, BL ^{[1
]}

Ganesan, A ^{[1
]}

机构：

[1] NATL UNIV SINGAPORE,INST MOL & CELL BIOL,CTR NAT PROD RES,SINGAPORE 119260,SINGAPORE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(97)00260-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A beta-amino alcohol library was prepared in solution by the lithium perchlorate promoted ring-opening of epoxides by primary and secondary amines. For increased efficiency in synthesis and screening, each reaction contained one epoxide and a pool of four amines. (C) 1997 Elsevier Science Ltd.

引用

页码：1511 / 1514

页数：4

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