Iron mobilization from ultraviolet-irradiated, iron-saturated, transferrin

被引：3

作者：

Aubailly, M

Salmon, S

Morliere, P

Haigle, J

Santus, R

机构：

[1] Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), Paris

[2] Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), 75231, Paris Cedex 05, 43, rue Cuvier

来源：

REDOX REPORT | 1996年 / 2卷 / 01期

关键词：

D O I：

10.1080/13510002.1996.11747025

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transferrin is the major iron transport protein of mammalian plasma. The ultraviolet-B irradiation of 1.4 mg/ml iron saturated transferrin solutions (similar to 32 mu M Fe3+) induces a Fe3+ loss accompanied by Fe2+ formation, The initial quantum yield of Fe3+ loss is wavelength dependent (phi(313 nm)similar to 1.3 x 10(-3)) and oxygen independent suggesting an intramolecular electron transfer from one of the Fe3+ Ligands. ii photolysis of tryptophan residues parallels this photoreduction.

引用

页码：41 / 45

页数：5

共 28 条

[1] IRON TRANSPORT AND STORAGE PROTEINS [J].

AISEN, P ;

LISTOWSKY, I .

ANNUAL REVIEW OF BIOCHEMISTRY, 1980, 49 :357-393

[2] FERROUS ION RELEASE FROM FERRITIN BY ULTRAVIOLET-A RADIATIONS [J].

AUBAILLY, M ;

SANTUS, R ;

SALMON, S .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1991, 54 (05) :769-773

[3] PEROXIDATION OF MODEL LIPOPROTEIN SOLUTIONS SENSITIZED BY PHOTOREDUCTION OF FERRITIN BY 365-NM RADIATION [J].

AUBAILLY, M ;

SALMON, S ;

HAIGLE, J ;

BAZIN, M ;

MAZIERE, JC ;

SANTUS, R .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1994, 26 (02) :185-191

[4] NEW PERSPECTIVES ON THE STRUCTURE AND FUNCTION OF TRANSFERRINS [J].

BAKER, EN ;

LINDLEY, PF .

JOURNAL OF INORGANIC BIOCHEMISTRY, 1992, 47 (3-4) :147-&

[5] DIRECT OBSERVATION OF MONOPHOTONIC PHOTO-IONIZATION IN TRYPTOPHAN EXCITED BY 300-NM RADIATION - A LASER PHOTOLYSIS STUDY [J].

BAZIN, M ;

PATTERSON, LK ;

SANTUS, R .

JOURNAL OF PHYSICAL CHEMISTRY, 1983, 87 (02) :189-190

[6]

BEILBY J, 1992, CLIN CHEM, V38, P2078

[7] CHRONIC ULTRAVIOLET RADIATION-INDUCED INCREASE IN SKIN IRON AND THE PHOTOPROTECTIVE EFFECT OF TOPICALLY APPLIED IRON CHELATORS [J].

BISSETT, DL ;

CHATTERJEE, R ;

HANNON, DP .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1991, 54 (02) :215-223

[8] FERROUS IRON RELEASE FROM TRANSFERRIN BY HUMAN NEUTROPHIL-DERIVED SUPEROXIDE ANION - EFFECT OF PH AND IRON SATURATION [J].

BRIELAND, JK ;

FANTONE, JC .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1991, 284 (01) :78-83

[9] SPECTROPHOTOMETRIC DETERMINATION OF SERUM IRON AT SUBMICROGRAM LEVEL WITH A NEW REAGENT (FERROZINE) [J].

CARTER, P .

ANALYTICAL BIOCHEMISTRY, 1971, 40 (02) :450-&

[10]

CHASTEEN ND, 1977, COORDIN CHEM REV, V22, P1

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