Synthesis and calorimetric investigation of unstable β-glycine

被引：52

作者：

Drebushchak, VA

Boldyreva, EV

Drebushchak, TN

Shutova, ES

机构：

[1] Novosibirsk State Univ, Novosibirsk 630090, Russia

[2] Russian Acad Sci, Siberian Branch, Inst Mineral & Petro, Novosibirsk 630090, Russia

[3] Russian Acad Sci, Siberian Branch, Inst State Chem & Mechanochem, Novosibirsk 630128, Russia

来源：

JOURNAL OF CRYSTAL GROWTH | 2002年 / 241卷 / 1-2期

关键词：

recrystallization; growth from solutions; organic compounds; drugs;

D O I：

10.1016/S0022-0248(02)01208-3

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

A new procedure for the synthesis of the unstable beta-polymorph of glycine has been developed. The amount of the sample synthesized in one run is enough to carry out the calorimetric measurements. The transformation of beta-glycine into alpha-glycine on heating was investigated. The transformation starts at 340 K as an exothermic process and takes some time for the completion. This agrees with the recent results of X-ray single crystal investigations showing that the beta-alpha transformation is the recrystallization. (C) 2002 Published by Elsevier Science B.V.

引用

页码：266 / 268

页数：3