The Role of Diet and Nutritional Intervention for the Management of Patients with NAFLD

被引:101
作者
Barrera, Francisco [1 ,2 ]
George, Jacob [1 ]
机构
[1] Univ Sydney, Westmead Hosp, Westmead Millennium Inst, Storr Liver Unit, Westmead, NSW 2145, Australia
[2] Pontificia Univ Catolica Chile, Dept Gastroenterol, Santiago 8330024, Chile
基金
英国医学研究理事会;
关键词
Nonalcoholic fatty liver; Macronutrients; Lifestyle intervention; Steatohepatitis; Mediterranean diet; Weight loss; Insulin resistance; FATTY LIVER-DISEASE; WEIGHT-LOSS MAINTENANCE; LOW-CARBOHYDRATE DIETS; SERUM ALANINE AMINOTRANSFERASE; CORONARY-HEART-DISEASE; NONALCOHOLIC STEATOHEPATITIS; CARDIOVASCULAR-DISEASE; VITAMIN-E; INSULIN SENSITIVITY; MEDITERRANEAN DIET;
D O I
10.1016/j.cld.2013.09.009
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
During the last few decades, the prevalence of obesity, insulin resistance and non-alcoholic fatty liver disease (NAFLD) have dramatically increased. Nutrition and modern lifestyle habits are intimately involved in this epidemiological change. Although lifestyle intervention can theoretically revert the metabolic disturbances and prevent the long-term complications of NAFLD, its efficacy is diminished in clinical practice by poor implementation and reduced adherence to lifestyle intervention programs. In this article we summarize the main elements of dietary interventions for NAFLD, describe practical strategies to optimize efficacy and review potential nutritional strategies under development that hopefully will improve outcomes in the future.
引用
收藏
页码:91 / +
页数:24
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