Spiro-gamma-lactone diterpenes from in vitro cultures of the liverwort, Heteroscyphus planus

被引：13

作者：

Nabeta, K ^{[1
]}

Oohata, T ^{[1
]}

Ohkubo, S ^{[1
]}

Sato, T ^{[1
]}

Katoh, K ^{[1
]}

机构：

[1] SHIONOGI ABURAHI LABS,KOHGA,SHIGA 52034,JAPAN

来源：

PHYTOCHEMISTRY | 1996年 / 41卷 / 02期

关键词：

Heteroscyphus planus; jungermanniales; suspension cultures; diterpenes; clerodanes; 3,4-epoxy-6,13-diacetoxy-5,10-trans-cleroda-14-en-20,12-olide; 3,4-epoxy-6-acetoxy-13-hydroxy-5,10-trans-cleroda-14-en-20,12-olide; 18-hydroxy-5,10-trans-cleroda-3,13E-dien-15-oic acid methyl ester;

D O I：

10.1016/0031-9422(95)00420-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new C-9-spiro-gamma-lactones of clerodane-type diterpenes, named heteroscypholide A and B, and one new cleroda-15-oic acid methyl ester were isolated from the cells of suspension culture of the liverwort, Heteroscyphus planus. The structures of heteroscypholide A and B and the cleroda-15-oic acid methyl ester were established as 3,4-epoxy-6,13-diacetoxy-5,10-trans-cleroda-14-en-20,12-olide 3,4-epoxy-6-acetoxy-13-hydroxy-5,10-trans-cleroda- 14-en-20,12-olide and 18-hydroxy-5,10-trans-cleroda-3,13E-dien-15-oic acid methyl ester, respectively. Their relative stereochemistry was determined on the basis of spectral analyses including X-ray crystallography and chemical correlation.

引用

页码：581 / 587

页数：7

共 17 条

[1] ENT-LABDANES AND FURANODITERPENES FROM THE LIVERWORT JAMESONIELLA-AUTUMNALIS [J].