Role of the sodium-hydrogen exchanger in ischemia-reperfusion injury in diabetes

被引:10
作者
Goel, DP
Pierce, GN
机构
[1] St Boniface Gen Hosp, Res Ctr, Div Stroke & Vasc Dis, Cell Biol Lab, Winnipeg, MB R2H 2A6, Canada
[2] Univ Manitoba, Dept Physiol, Winnipeg, MB, Canada
关键词
sodium-hydrogen exchange; ischemia-reperfusion injury; diabetes;
D O I
10.1023/A:1008994631084
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ischemic heart disease is a significant problem in the diabetic population. Animal models of diabetes show a paradoxical resistance to ischemic challenge. The present treatise will discuss the mechanics involved and the central role that Na+-H+ exhanger plays in this response to ischemic-reperfusion injury.
引用
收藏
页码:45 / 51
页数:7
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