Interaction of polyelectrolytes and their composites with living cells

被引：103

作者：

Chanana, M

Gliozzi, A

Diaspro, A

Chodnevskaja, I

Huewel, S

Moskalenko, V

Ulrichs, K

Galla, HJ

Krol, S ^{[1
]}

机构：

[1] Univ Genoa, Dept Phys, CNR, INFM, I-16146 Genoa, Italy

[2] Univ Munster, Dept Biochem, D-48149 Munster, Germany

[3] Univ Wurzburg Hosp, Dept Surg, D-97080 Wurzburg, Germany

来源：

NANO LETTERS | 2005年 / 5卷 / 12期

关键词：

D O I：

10.1021/nl0521219

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Since the layer-wise polyelectrolyte deposition offers the opportunity to modify surfaces for biomedical applications, interactions and toxicity between polyelectrolytes and living cells become interesting. The aim of the present work is to determine the different factors such as contact area, charge, and transplantation site that influence the cell reaction to a specific polymer. We found that toxicity is influenced by all these factors and cannot be tested easily in a model.

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页码：2605 / 2612

页数：8

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