Noninvasive Prenatal Testing for Fetal Aneuploidy

被引：288

作者：

不详

机构：

来源：

OBSTETRICS AND GYNECOLOGY | 2012年 / 120卷 / 06期

关键词：

MATERNAL PLASMA; DNA; DIAGNOSIS;

D O I：

10.1097/01.AOG.0000423819.85283.f4

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Noninvasive prenatal testing that uses cell free fetal DNA from the plasma of pregnant women offers tremendous potential as a screening tool for fetal aneuploidy. Cell free fetal DNA testing should be an informed patient choice after pretest counseling and should not be part of routine prenatal laboratory assessment. Cell free fetal DNA testing should not be offered to low-risk women or women with multiple gestations because it has not been sufficiently evaluated in these groups. A negative cell free fetal DNA test result does not ensure an unaffected pregnancy. A patient with a positive test result should be referred for genetic counseling and should be offered invasive prenatal diagnosis for confirmation of test results.

引用

页码：1532 / 1534

页数：3

共 14 条

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