Human synaptotagmin V (SYT5): Sequence, genomic structure, and chromosomal location

被引：8

作者：

Craxton, M ^{[1
]}

Olsen, A ^{[1
]}

Goedert, M ^{[1
]}

机构：

[1] LAWRENCE LIVERMORE NATL LAB,CTR HUMAN GENOME,BIOL & BIOTECHNOL RES PROGRAM,LIVERMORE,CA 94550

来源：

GENOMICS | 1997年 / 42卷 / 01期

关键词：

D O I：

10.1006/geno.1997.4722

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have determined the sequence, genomic structure, and chromosomal location of the human synaptotagmin V (SYTV) gene. The human SYTV gene encodes a 386-amino-acid product which is 91% identical to rat Syt V. The human SYTV open reading frame is interrupted by seven introns which can be alternatively spliced, Human SYTV was found to lie very close to SYTIII on chromosome 19q13.4 by PCR analysis of somatic cell hybrid DNA and by DNA hybridization to arrayed cosmids of the chromosome 19 metric physical map. This provides the first report of linked synaptotagmin genes. (C) 1997 Academic Press.

引用

页码：165 / 169

页数：5

共 30 条

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