Use of ALA and ALA derivatives for optimizing ALA-based photodynamic therapy: A review of our experience

被引:11
作者
Fukuda, H
Casas, A
Batlle, A
机构
[1] Consejo Nacl Invest Cient & Tecn, Ctr Invest Sobre Porfirinas & Porfirias, CIPYP, RA-1056 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, RA-1056 Buenos Aires, DF, Argentina
关键词
photodynamic therapy; 5-aminolevulinic acid; ALA esters; porphyrins; protoporphyrin IX;
D O I
10.1615/JEnvironPatholToxicolOncol.v25.i1-2.70
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
5-Aminolevulinic acid (ALA)-based PDT has been gaining increased attention in the last ten years, and become an approved treatment modality for some cancers and other diseases. Different approaches to enhance this therapeutic modality are in progress, including the development of several drug delivery systems and the use of more lipophilic ALA derivatives. This paper focuses on our experience in this field.
引用
收藏
页码:127 / 143
页数:19
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