Preliminary assessment of genome differences between the reference nine mile isolate and two human endocarditis isolates of Coxiella burnetii

被引:6
作者
Beare, Paul A.
Porcella, Stephen F.
Seshadri, Rekha
Samuel, James E.
Heinzen, Robert A.
机构
[1] NIAID, Rocky Mt Lab, Genom Core Facil, NIH, Hamilton, MT 59840 USA
[2] NIAID, Intracellular Parasites Lab, Coxiella Pathogenesis Sect, NIH, Hamilton, MT 59840 USA
[3] Inst Genom Res, Rockville, MD 20850 USA
[4] Texas A&M Univ, Dept Med & Microbiol Immunobiol, College Stn, TX 77843 USA
来源
RICKETTSIOSES: FROM GENOME TO PROTEOME, PATHOBIOLOGY, AND RICKETTSIAE AS AN INTERNATIONAL THREAT | 2005年 / 1063卷
关键词
endocarditis; genome; sequencing; Q fever; comparative genomics;
D O I
10.1196/annals.1355.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This study investigates the complete genome sequences of the Nine Mile, K, and G isolates to improve our understanding of the unique virulence properties of C. burnetii and to provide important insight into the genome architecture and genetic diversity of this pathogen.
引用
收藏
页码:64 / 67
页数:4
相关论文
共 7 条
  • [1] Improved microbial gene identification with GLIMMER
    Delcher, AL
    Harmon, D
    Kasif, S
    White, O
    Salzberg, SL
    [J]. NUCLEIC ACIDS RESEARCH, 1999, 27 (23) : 4636 - 4641
  • [2] Developmental biology of Coxiella burnetii
    Heinzen, RA
    Hackstadt, T
    Samuel, JE
    [J]. TRENDS IN MICROBIOLOGY, 1999, 7 (04) : 149 - 154
  • [3] DIFFERENTIATION OF COXIELLA-BURNETII ISOLATES BY ANALYSIS OF RESTRICTION-ENDONUCLEASE-DIGESTED DNA SEPARATED BY SDS-PAGE
    HENDRIX, LR
    SAMUEL, JE
    MALLAVIA, LP
    [J]. JOURNAL OF GENERAL MICROBIOLOGY, 1991, 137 : 269 - 276
  • [4] Q fever
    Maurin, M
    Raoult, D
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 1999, 12 (04) : 518 - +
  • [5] CORRELATION OF PLASMID TYPE AND DISEASE CAUSED BY COXIELLA-BURNETII
    SAMUEL, JE
    FRAZIER, ME
    MALLAVIA, LP
    [J]. INFECTION AND IMMUNITY, 1985, 49 (03) : 775 - 779
  • [6] Complete genome sequence of the Q-fever pathogen Coxiella burnetii
    Seshadri, R
    Paulsen, IT
    Eisen, JA
    Read, TD
    Nelson, KE
    Nelson, WC
    Ward, NL
    Tettelin, H
    Davidsen, TM
    Beanan, MJ
    Deboy, RT
    Daugherty, SC
    Brinkac, LM
    Madupu, R
    Dodson, RJ
    Khouri, HM
    Lee, KH
    Carty, HA
    Scanlan, D
    Heinzen, RA
    Thompson, HA
    Samuel, JE
    Fraser, CM
    Heidelberg, JF
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (09) : 5455 - 5460
  • [7] Plasmid-homologous sequences in the chromosome of plasmidless Coxiella burnetii Scurry Q217
    Willems, H
    Ritter, M
    Jager, C
    Thiele, D
    [J]. JOURNAL OF BACTERIOLOGY, 1997, 179 (10) : 3293 - 3297