Archaeal DNA replication and repair

被引:117
作者
Kelman, Z
White, MF
机构
[1] Univ Maryland, Maryland Biotechnol Inst, Ctr Adv Res Biotechnol, Rockville, MD 20850 USA
[2] Univ St Andrews, Ctr Biomol Sci, St Andrews KY16 9ST, Fife, Scotland
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.mib.2005.10.001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Since the first archaeal genome was sequenced, much attention has been focused on the study of these unique microorganisms. We have learnt that although archaeal DNA metabolic processes (replication, recombination and repair) are more similar to the metabolic processes of Eukarya than those of Bacteria, Archaea are not simply 'mini Eukarya'. They are, in fact, a mosaic of the eukaryal and bacterial systems that also possess archaeal-specific features. Recent biochemical and structural studies of the proteins that participate in archaeal DNA replication and repair have increased our understanding of these processes.
引用
收藏
页码:669 / 676
页数:8
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