Pain

被引：21

作者：

Wood, JN

Perl, ER

机构：

[1] UCL, Dept Biol, London WC1E 6BT, England

[2] Univ N Carolina, Dept Cell & Mol Physiol, Chapel Hill, NC 27599 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1999年 / 9卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0959-437X(99)80049-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Advances in our understanding of the activation of peripheral damage-sensing neurons (nociceptors) over the past year have been complemented by electrophysiological and imaging studies of central nervous system pain-related centres. The manipulation of gene expression in a reversible and cell type specific way combined with imaging and electrophysiological studies holds promise for helping us to identify the spatial and molecular substrates of pain perception with increasing precision and gives hope for improved analgesic therapies.

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收藏

页码：328 / 332

页数：5

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