Cell signaling: Life or death decisions of Ras proteins

被引：73

作者：

Feig, LA ^{[1
]}

Buchsbaum, RJ

机构：

[1] Tufts Univ, Sch Med, Dept Biochem, Boston, MA 02111 USA

[2] Tufts Univ New England Med Ctr, Div Hematol Oncol, Boston, MA 02111 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 07期

关键词：

D O I：

10.1016/S0960-9822(02)00787-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The discovery of a new downstream target for the Ras GTPases - a Nore1-Mst1 protein complex reveals a mechanism by which Ras can promote apoptosis, and suggests that the influence of Ras on cell survival or death depends upon the relative level of activation of its various target proteins.

引用

页码：R259 / R261

页数：3

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