Effect of solvent quality on the molecular dimensions of PAMAM dendrimers

被引：114

作者：

Topp, A

Bauer, BJ

Tomalia, DA

Amis, EJ ^{[1
]}

机构：

[1] Natl Inst Stand & Technol, Gaithersburg, MD 20899 USA

[2] Michigan Mol Inst, Midland, MI 48640 USA

来源：

MACROMOLECULES | 1999年 / 32卷 / 21期

关键词：

D O I：

10.1021/ma9901240

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The average dimensions of poly(amido amine) (PAMAM) dendrimers of generations G5 and G8 are studied by small-angle neutron scattering (SANS) asa function of solvents of differing quality, the composition of mixtures of a good solvent and a nonsolvent, and temperature. The radius of gyration, R-g, of the G8 dendrimer decreases for the series of solvents D(CD2)(m)OD (with m = 0, 1, 2, 4) by approximately 10% from m = 0 to m= 4 with decreasing solvent quality. The average segment density in solution is calculated for G5 and Gs. The size of PAMAM dendrimers, as reflected by R-g, is not influenced by the composition of mixtures of methyl alcohol/acetone in the full range of solubility of the dendrimers. In the temperature range =10 degrees C less than or equal to T less than or equal to 50 degrees C,the dimensions of the G8 and G5 dendrimer are constant, within approximate to 5% of each other.

引用

页码：7232 / 7237

页数：6

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