MULTOVL: fast multiple overlaps of genomic regions

被引：26

作者：

Aszodi, Andras ^{[1
]}

机构：

[1] Campus Sci Support Facil, Sci Comp Core Facil, A-1030 Vienna, Austria

来源：

BIOINFORMATICS | 2012年 / 28卷 / 24期

关键词：

D O I：

10.1093/bioinformatics/bts607

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present the MULTOVL application suite that detects and statistically analyses multiple overlaps of genomic regions in a fast and efficient manner. The package supports the detection of multiple region intersections, unions and 'solitary' genomic regions. The significance of actually observed overlaps is estimated by comparing them with empirical null distributions generated by random shuffling of the input regions.

引用

页码：3318 / 3319

页数：2

共 3 条

[1] Intergenic Polycomb target sites are dynamically marked by non-coding transcription during lineage commitment [J].

Hekimoglu-Balkan, Betuel ;

Aszodi, Andras ;

Heinen, Robert ;

Jaritz, Markus ;

Ringrose, Leonie .

RNA BIOLOGY, 2012, 9 (03) :314-325

[2] BEDTools: a flexible suite of utilities for comparing genomic features [J].

Quinlan, Aaron R. ;

Hall, Ira M. .

BIOINFORMATICS, 2010, 26 (06) :841-842

[3] The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis [J].

Revilla-i-Domingo, Roger ;

Bilic, Ivan ;

Vilagos, Bojan ;

Tagoh, Hiromi ;

Ebert, Anja ;

Tamir, Ido M. ;

Smeenk, Leonie ;

Trupke, Johanna ;

Sommer, Andreas ;

Jaritz, Markus ;

Busslinger, Meinrad .

EMBO JOURNAL, 2012, 31 (14) :3130-3146

← 1 →