A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate

被引：51

作者：

Yum, JH

Yong, DG

Lee, K

Kim, HS

Chong, YS

机构：

[1] Yonsei Univ, Coll Med, Dept Clin Pathol, Res Inst Bacterial Resistance, Seoul, South Korea

[2] Yonsei Univ, Coll Med, Brain Korea 21 Project Med Sci, Seoul, South Korea

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2002年 / 42卷 / 03期

关键词：

D O I：

10.1016/S0732-8893(01)00352-2

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a bla(VIM-2) gene cassette on a class I integron. This finding indicates that bla(VIM-2) is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC. (C) 2002 Elsevier Science Inc. All rights reserved.

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页码：217 / 219

页数：3

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