Different localization of the MPB70 and MPB83 proteins of Mycobacterium bovis

被引：3

作者：

Harboe, M

Wiker, HG

机构：

[1] Institute of Immunology and Rheumatology, University of Oslo

来源：

MEDICAL PRINCIPLES AND PRACTICE | 1997年 / 6卷 / 02期

关键词：

Mycobacterium bovis; secreted proteins lipoproteins; MPB70; MPB83;

D O I：

10.1159/000157431

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

MPB70 and MPB83 are similar but clearly distinct proteins. MPB70 is a typical secreted protein while the mpb83 and mpt83 genes contain a typical lipoprotein consensus element absent in mpb70. We show here that 26-kD MPB83 behaves as a lipoprotein upon detergent extraction and that the MPB70/MPB83 pair can be used as marker proteins for characterization of protein localization in relation to the mycobacterial cell.

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页码：84 / 90

页数：7

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