Zirconium(IV) chloride catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones

被引：388

作者：

Reddy, CV ^{[1
]}

Mahesh, M ^{[1
]}

Raju, PVK ^{[1
]}

Babu, TR ^{[1
]}

Reddy, VVN ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 2, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 14期

关键词：

zirconium tetrachloride; beta-ketoesters; Biginelli reaction; dihydropyrimidinones;

D O I：

10.1016/S0040-4039(02)00280-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zirconium tetrachloride catalyzes efficiently the three component condensation reaction of an aromatic aldehyde, a beta-ketoester and urea in refluxing ethanol to afford the corresponding dihydropyrimidinone in high yield. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2657 / 2659

页数：3

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