Efficient highly diastereoselective synthesis of 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazines

被引：91

作者：

Adib, M

Sheibani, E

Mostofi, M

Ghanbary, K

Bijanzadeh, HR

机构：

[1] Univ Tehran, Fac Sci, Dept Chem, Tehran, Iran

[2] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON | 2006年 / 62卷 / 14期

关键词：

diastereoselective synthesis; pyridine carboxaldehydes; acetylenic esters; 1-alkyl imidazoles; 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazines;

D O I：

10.1016/j.tet.2006.01.048

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Alkyl imidazoles react smoothly with dialkyl acetylenedicarboxylates in the presence of pyridine carboxaldehydes to diastereoselectively produce 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazine derivatives in excellent yields. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3435 / 3438

页数：4

共 20 条

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