Thiazolidinediones: Do harms outweigh benefits?

被引:19
作者
Lipscombe, Lorraine L. [1 ,2 ]
机构
[1] Univ Toronto, Inst Clin Evaluat Sci, Dept Med, Toronto, ON M4N 3M5, Canada
[2] Womens Coll Hosp, Toronto, ON M5S 1B2, Canada
关键词
CARDIOVASCULAR EVENTS; METAANALYSIS; RISK; ROSIGLITAZONE; PIOGLITAZONE; TRIALS; DEATH;
D O I
10.1503/cmaj.081713
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:16 / 17
页数:2
相关论文
共 9 条
[1]
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events):: a randomised controlled trial [J].
Dormandy, JA ;
Charbonnel, B ;
Eckland, DJA ;
Erdmann, E ;
Massi-Benedetti, M ;
Kmoules, IK ;
Skene, AM ;
Tan, MH ;
Lefébvre, PJ ;
Murray, GD ;
Standl, E ;
Wilcox, RG ;
Wlhelmsen, L ;
Betteridge, J ;
Birkeland, K ;
Golay, A ;
Heine, RJ ;
Korányi, L ;
Laakso, M ;
Mokán, M ;
Norkus, A ;
Pirags, V ;
Podar, T ;
Scheen, A ;
Scherbaum, W ;
Schernthaner, G ;
Schmitz, O ;
Skrha, J ;
Smith, U ;
Taton, J .
LANCET, 2005, 366 (9493) :1279-1289
[2]
Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials [J].
Lago, Rodrigo M. ;
Singh, Premranjan P. ;
Nesto, Richard W. .
LANCET, 2007, 370 (9593) :1129-1136
[3]
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus - A meta-analysis of randomized trials [J].
Lincoff, A. Michael ;
Wolski, Kathy ;
Nicholls, Stephen J. ;
Nissen, Steven E. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (10) :1180-1188
[4]
Thiazolidinediones and cardiovascular outcomes in older patients with diabetes [J].
Lipscombe, Lorraine L. ;
Gomes, Tara ;
Levesque, Linda E. ;
Hux, Janet E. ;
Juurlink, David N. ;
Alter, David A. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (22) :2634-2643
[5]
Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis [J].
Loke, Yoon K. ;
Singh, Sonal ;
Furberg, Curt D. .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2009, 180 (01) :32-39
[6]
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes (vol 356, pg 2457, 2007) [J].
Nissen, Steven E. ;
Wolski, Kathy .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (24) :2457-2471
[7]
Long-term risk of cardiovascular events with rosiglitazone - A meta-analysis [J].
Singh, Sonal ;
Loke, Yoon K. ;
Furberg, Curt D. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (10) :1189-1195
[8]
US Food and Drug Administration, 2018, FDA BRIEF DOC JOINT
[9]
Drug therapy: Thiazolidinediones [J].
Yki-Jarvinen, H .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (11) :1106-1118