Six new 2-(2-phenylethyl)chromones from agarwood

被引：57

作者：

Konishi, T ^{[1
]}

Konoshima, T

Shimada, Y

Kiyosawa, S

机构：

[1] Kyoto Pharmaceut Univ, Yamashima Ku, Kyoto 6078414, Japan

[2] Mitsubishi Pharmaceut Co, Gose 6392216, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2002年 / 50卷 / 03期

关键词：

Aquilaria malaccensis; Aquilaniaceae; agarwood; 2-(2-phenylthyl)chromone; flidersiachromone;

D O I：

10.1248/cpb.50.419

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Six new chromones, 6-methoxy-2-[2-(3-methoxy-4-hydroxyphenyl)ethyl]chromone (2), 6,8-dihydroxy-2-(2phenylethyl)chromone (3), 6-hydroxy-2-[2-(.4-hydroxyphenyl)ethyl]chromone (4), 6-hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone (5), 7-hydroxy-2-(2-phenylethyl)chromone (6), and 6-hydroxy-7-methoxy-2-(2-phenylethyl)chromone (7) were isolated from the ether extract of agarwood in addition to a known compound, 2-(2phenylethyl)chromone or flidersiachromone (1). Their structures were determined by spectroscopic methods including UV, IR, and NMR spectral data and comparisons with the! calculated values using the hydroxyl and methoxyl substituent increments of the chromone ring.

引用

页码：419 / 422

页数：4

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