Selective adsorption of bilirubin by macroporous poly(glycidyl methacrylate-co-divinylbenzene) beads

被引：10

作者：

Kuroda, H ^{[1
]}

Tanaka, T ^{[1
]}

Osawa, Z ^{[1
]}

机构：

[1] GUNMA UNIV,FAC ENGN,KIRYU,GUMMA 376,JAPAN

来源：

ANGEWANDTE MAKROMOLEKULARE CHEMIE | 1996年 / 237卷

关键词：

D O I：

10.1002/apmc.1996.052370108

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Macroporous glycidyl methacrylate (GMA)-divinylbenzene (DVB) copolymer beads have been synthesized and the adsorption of bilirubin, albumin and other serum components were studied. The beads composed of DVB/GMA in the weight ratio of 75/25 provide an excellent bilirubin adsorption ability. When the surface of the beads was previously coated with albumin, discriminating adsorption of the bilirubin in the serum was attained and the adsorption of albumin was depressed. Ln addition, when the coated albumin was crosslinked with glutaraldehyde, the excellent bilirubin adsorption ability was maintained, however, an adsorption of albumin from the serum occurred.

引用

页码：143 / 161

页数：19

共 25 条

[1] THE INTERACTION OF PLASMA-PROTEINS WITH POLYMERS .1. RELATIONSHIP BETWEEN POLYMER SURFACE-ENERGY AND PROTEIN ADSORPTION-DESORPTION [J].