Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1

被引：30

作者：

Lin, CT ^{[1
]}

Huang, YJ ^{[1
]}

Chu, PH ^{[1
]}

Hsu, JL ^{[1
]}

Huang, CH ^{[1
]}

Peng, HL ^{[1
]}

机构：

[1] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 30050, Taiwan

来源：

RESEARCH IN MICROBIOLOGY | 2006年 / 157卷 / 02期

关键词：

HptB; hybrid sensor PA 1611; Pseudomonas aeruginosa PAO1;

D O I：

10.1016/j.resmic.2005.06.012

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We herein demonstrate that the hybrid sensor PA1611 carries out specific signal transduction, through HptB (PA3345), to the response regulator PA3346 in Pseudomonas aeruginosa PAO1. As assessed by phenotypic changes in the hptB deletion mutant, the pathway is likely to be involved in the regulation of flagellar activity, the chemotaxis response, twitching motility, and biofilm formation in the bacteria. (c) 2005 Elsevier SAS. All rights reserved.

引用

页码：169 / 175

页数：7

共 22 条

[1]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[2] Evolutionary analysis of the two-component systems in Pseudomonas aeruginosa PAO1 [J].

Chen, YT ;

Chang, HY ;

Lu, CL ;

Peng, HL .

JOURNAL OF MOLECULAR EVOLUTION, 2004, 59 (06) :725-737

[3] A four-tiered transcriptional regulatory circuit controls flagellar biogenesis in Pseudomonas aeruginosa [J].

Dasgupta, N ;

Wolfgang, MC ;

Goodman, AL ;

Arora, SK ;

Jyot, J ;

Lory, S ;

Ramphal, R .

MOLECULAR MICROBIOLOGY, 2003, 50 (03) :809-824

[4]

DAZINS A, 1993, J BACTERIOL, V175, P5934

[5] Initiation of biofilm formation by Pseudomonas aeruginosa 57RP correlates with emergence of hyperpiliated and highly adherent phenotypic variants deficient in swimming, swarming, and twitching motilities [J].

Déziel, E ;

Comeau, Y ;

Villemur, R .

JOURNAL OF BACTERIOLOGY, 2001, 183 (04) :1195-1204

[6] Cluster II che genes from Pseudomonas aeruginosa are required for an optimal chemotactic response [J].

Ferrández, A ;

Hawkins, AC ;

Summerfield, DT ;

Harwood, CS .

JOURNAL OF BACTERIOLOGY, 2002, 184 (16) :4374-4383

[7] EFFECTS OF CULTURE CONCENTRATION AND AGE, TIME, AND TEMPERATURE ON BACTERIAL ATTACHMENT TO POLYSTYRENE [J].

FLETCHER, M .

CANADIAN JOURNAL OF MICROBIOLOGY, 1977, 23 (01) :1-6

[8] MOLECULAR-CLONING OF THE PLASMID RP4 PRIMASE REGION IN A MULTI-HOST-RANGE TACP EXPRESSION VECTOR [J].

FURSTE, JP ;

PANSEGRAU, W ;

FRANK, R ;

BLOCKER, H ;

SCHOLZ, P ;

BAGDASARIAN, M ;

LANKA, E .

GENE, 1986, 48 (01) :119-131

[9] Two-component and phosphorelay signal transduction [J].

Hoch, JA .

CURRENT OPINION IN MICROBIOLOGY, 2000, 3 (02) :165-170

[10] Phosphorylation of the response regulator CheV is required for adaptation to attractants during Bacillus subtilis chemotaxis [J].

Karatan, E ;

Saulmon, MM ;

Bunn, MW ;

Ordal, GW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (47) :43618-43626

← 1 2 3 →