Attempted and completed suicides after subthalamic nucleus stimulation for Parkinson's disease
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作者:
Soulas, T.
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CHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
CHU Henri Mondor, Dept Neurosurg, AP HP, F-94000 Creteil, FranceCHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
Soulas, T.
[1
,2
]
Gurruchaga, J-M
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CHU Henri Mondor, Dept Neurosurg, AP HP, F-94000 Creteil, FranceCHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
Gurruchaga, J-M
[2
]
Palfi, S.
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机构:
CHU Henri Mondor, Dept Neurosurg, AP HP, F-94000 Creteil, FranceCHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
Palfi, S.
[2
]
Cesaro, P.
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CHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, FranceCHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
Cesaro, P.
[1
]
Nguyen, J-P
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CHU Henri Mondor, Dept Neurosurg, AP HP, F-94000 Creteil, FranceCHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
Nguyen, J-P
[2
]
Fenelon, G.
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CHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, FranceCHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
Fenelon, G.
[1
]
机构:
[1] CHU Henri Mondor, Dept Neurol, AP HP, F-94000 Creteil, France
[2] CHU Henri Mondor, Dept Neurosurg, AP HP, F-94000 Creteil, France
A higher than expected frequency of suicide has been reported among patients undergoing subthalamic nucleus deep brain stimulation (STN DBS) for advanced Parkinson's disease (PD). We conducted a retrospective survey of 200 patients with PD who underwent STN DBS. Two patients (1%) committed suicide and four (2%) attempted suicide, despite clear motor improvements. Suicidal patients did not differ from non-suicidal patients with respect to age, disease duration or preoperative depressive and cognitive status. Suicidal behaviour was associated with postoperative depression and/or altered impulse regulation. Suicidal behaviour is a potential hazard of STN DBS, calling for careful preoperative assessment and close postoperative psychiatric and behavioural follow- up.