Transcriptional activation of mRNA of intercellular adhesion molecule 1 and induction of its cell surface expression in normal human gingival fibroblasts by Mycoplasma salivarium and Mycoplasma fermentans

被引：19

作者：

Dong, L

Shibata, KI

Sawa, Y

Hasebe, A

Yamaoka, Y

Yoshida, S

Watanabe, T

机构：

[1] Hokkaido Univ, Sch Dent, Dept Oral Bacteriol, Kita Ku, Sapporo, Hokkaido 0608586, Japan

[2] Hokkaido Univ, Sch Dent, Dept Oral Anat 1, Kita Ku, Sapporo, Hokkaido 0608586, Japan

[3] Hokkaido Univ, Sch Dent, Dept Prosthet Dent, Kita Ku, Sapporo, Hokkaido 0608586, Japan

来源：

INFECTION AND IMMUNITY | 1999年 / 67卷 / 06期

关键词：

D O I：

10.1128/IAI.67.6.3061-3065.1999

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Lipoproteins in the cell membranes of both Mycoplasma salivarium and Mycoplasma fermentans were demonstrated to trigger the transcription of intercellular adhesion molecule-1 mRNA in normal fibroblasts isolated from human gingival tissue and to induce its cell surface expression by a mechanism distinct from that of Escherichia call lipopolysaccharide. The lipid moiety of the lipoproteins was suggested to play a key role in the expression of the activity.

引用

页码：3061 / 3065

页数：5

共 36 条

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