Size Alters Susceptibility of Vectors to Dengue Virus Infection and Dissemination

被引:123
作者
Alto, Barry W. [1 ]
Reiskind, Michael H. [1 ]
Lounibos, L. Philip [1 ]
机构
[1] Univ Florida, Florida Med Entomol Lab, Vero Beach, FL USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
D O I
10.4269/ajtmh.2008.79.688
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The size of arthropod vectors may affect their ability to transmit pathogens. Here we test the hypothesis that body size alters the Susceptibility of Aedes aegypti and Aedes albopictus mosquitoes to dengue virus (DENV) infection and subsequent dissemination throughout the body of the mosquito. After feeding on blood containing known quantities of virus, smaller-size females were significantly more likely to become infected and to disseminate virus than larger individuals. The effects of size were stronger for Ae. aegypti and independent of rearing conditions. Ae. albopictus was more susceptible to DENV infection and had higher virus titer in the body than Ae. aegypti, yet infected Ae. aegypti disseminated DENV more readily than infected Ae. albopictus. These results are consistent with the concept that lie. aegypti is a more competent vector of DENV and emphasize the importance of body size in determining adult infection parameters.
引用
收藏
页码:688 / 695
页数:8
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