Spectacular induced-fit process for guest binding by a calix[6]arene Zn(II) funnel complex

被引：27

作者：

Coquiere, David ^{[1
]}

Marrot, Jerome ^{[2
]}

Reinaud, Olivia ^{[1
]}

机构：

[1] Univ Paris 05, CNRS, UMR 8601, Chim & Biochim Pharmacol & Toxicol Lab, F-75006 Paris, France

[2] Univ Versailles St Quentin Yvelines, CNRS, UMR 8180, Inst Lavoisier Versailles, F-78035 Versailles, France

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2008年 / 6卷 / 21期

关键词：

D O I：

10.1039/b809699f

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The host properties of a calix[6]arene cone capped by a Zn(II) tris-imidazole core at the small rim and decorated by three NH2 substituents at the large rim are described and compared to the hexa-tBu parent complex. It is shown that the replacement of three bulky tBu substituents by three hydrophilic and small NH2 groups has three major impacts: the receptor is now soluble in aqueous media, it accepts large guests such as dimethyldopamine and, most interestingly, undergoes a spectacular induced-fit behavior for guest binding.

引用

收藏

页码：3930 / 3934

页数：5

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